Mixed Brain Pathologies in Dementia : The BrainNet Europe Consortium Experience
Identifieur interne : 002511 ( Main/Exploration ); précédent : 002510; suivant : 002512Mixed Brain Pathologies in Dementia : The BrainNet Europe Consortium Experience
Auteurs : Gabor G. Kovacs [Autriche, Hongrie] ; Irina Alafuzoff [Finlande] ; Safa Al-Sarraj [Royaume-Uni] ; Thomas Arzberger [Allemagne] ; Nenad Bogdanovic [Suède] ; Sabina Capellari [Italie] ; Isidro Ferrer [Espagne] ; Ellen Gelpi [Autriche] ; Viktor Kövari [Hongrie] ; Hans Kretzschmar [Allemagne] ; Zoltan Nagy [Hongrie] ; Piero Parchi [Italie] ; Danielle Seilhean [France] ; Hilkka Soininen [Finlande] ; Claire Troakes [Royaume-Uni] ; Herbert Budka [Autriche]Source :
- Dementia and geriatric cognitive disorders [ 1420-8008 ] ; 2008.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Background: Dementia results from heterogeneous diseases of the brain. Mixed disease forms are increasingly recognized. Methods: We performed a survey within brain banks of BrainNet Europe to estimate the proportion of mixed disease forms underlying dementia and age- and gender-specific influences. Results: Data collected in 9 centres from 3,303 individuals were analysed. The proportion of patients with mixed diagnoses among all cases with Alzheimer disease (AD), vascular pathology (VP), argyrophilic grain dementia (AGD), and synucleinopathies, such as Lewy body dementia (LBD), Parkinson disease (PD) and synuclein pathology only in the amygdala, was 53.3%. Mixed pathology was more frequently reported with LBD, PD, AGD, and VP than with AD. The percentage of mixed diagnoses for AGD and VP significantly differed between centres. In patients younger than 75 years, synucleinopathies, and pure forms of AD, VP, and AGD were more frequent in men. Above 75 years of age, more women had pure AD and pure AGD. Conclusions: The most obvious neuropathological alteration should not terminate the diagnostic procedure since copathology is likely to be found. Neuropathological interpretation of AGD and VP has not been sufficiently established in a consensus. Pure forms of synucleinopathies are unlikely sole substrates for dementia.
Affiliations:
- Allemagne, Autriche, Espagne, Finlande, France, Hongrie, Italie, Royaume-Uni, Suède
- Angleterre, Bavière, Catalogne, District de Haute-Bavière, Grand Londres, Hongrie centrale, Svealand, Vienne (Autriche), Émilie-Romagne, Île-de-France
- Barcelone, Bologne, Budapest, Londres, Munich, Paris, Stockholm, Vienne (Autriche)
- Université Louis-et-Maximilien de Munich, Université de Bologne
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type="region">Émilie-Romagne</region></placeName><orgName type="university">Université de Bologne</orgName></affiliation></author><author><name sortKey="Ferrer, Isidro" sort="Ferrer, Isidro" uniqKey="Ferrer I" first="Isidro" last="Ferrer">Isidro Ferrer</name><affiliation wicri:level="3"><inist:fA14 i1="10"><s1>Institute of Neuropathology, IDIBELL-Hospital Universitari de Bellvitge, Hospitalet de Llobregat</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>7 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Gelpi, Ellen" sort="Gelpi, Ellen" uniqKey="Gelpi E" first="Ellen" last="Gelpi">Ellen Gelpi</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Institute of Neurology, Medical University of Vienna</s1><s2>Vienna</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>8 aut.</sZ><sZ>16 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München</s1><s2>Munich</s2><s3>DEU</s3><sZ>4 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Nagy, Zoltan" sort="Nagy, Zoltan" uniqKey="Nagy Z" first="Zoltan" last="Nagy">Zoltan Nagy</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Former National Institute of Psychiatry and Neurology</s1><s2>Budapest</s2><s3>HUN</s3><sZ>1 aut.</sZ><sZ>9 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Hongrie</country><placeName><settlement type="city">Budapest</settlement><region nuts="2">Hongrie centrale</region></placeName></affiliation></author><author><name sortKey="Parchi, Piero" sort="Parchi, Piero" uniqKey="Parchi P" first="Piero" last="Parchi">Piero 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sortKey="Soininen, Hilkka" sort="Soininen, Hilkka" uniqKey="Soininen H" first="Hilkka" last="Soininen">Hilkka Soininen</name><affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Department of Neurology, Kuopio University Hospital</s1><s2>Kuopio</s2><s3>FIN</s3><sZ>14 aut.</sZ></inist:fA14><country>Finlande</country><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Troakes, Claire" sort="Troakes, Claire" uniqKey="Troakes C" first="Claire" last="Troakes">Claire Troakes</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>MRC Neurodegenerative Brain Bank, Institute of Psychiatry, Kings College</s1><s2>London</s2><s3>GBR</s3><sZ>3 aut.</sZ><sZ>15 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Budka, Herbert" sort="Budka, Herbert" uniqKey="Budka H" first="Herbert" last="Budka">Herbert Budka</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Institute of Neurology, Medical University of Vienna</s1><s2>Vienna</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>8 aut.</sZ><sZ>16 aut.</sZ></inist:fA14><country>Autriche</country><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">08-0508198</idno><date when="2008">2008</date><idno type="stanalyst">PASCAL 08-0508198 INIST</idno><idno type="RBID">Pascal:08-0508198</idno><idno type="wicri:Area/PascalFrancis/Corpus">000835</idno><idno type="wicri:Area/PascalFrancis/Curation">000B74</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000743</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000743</idno><idno 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Kovacs</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Institute of Neurology, Medical University of Vienna</s1><s2>Vienna</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>8 aut.</sZ><sZ>16 aut.</sZ></inist:fA14><country>Autriche</country><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Former National Institute of Psychiatry and Neurology</s1><s2>Budapest</s2><s3>HUN</s3><sZ>1 aut.</sZ><sZ>9 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Hongrie</country><placeName><settlement type="city">Budapest</settlement><region nuts="2">Hongrie centrale</region></placeName></affiliation></author><author><name sortKey="Alafuzoff, Irina" sort="Alafuzoff, Irina" uniqKey="Alafuzoff I" first="Irina" last="Alafuzoff">Irina Alafuzoff</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>department of Clinical Medicine, Unit of Neurology, Kuopio University</s1><s3>FIN</s3><sZ>2 aut.</sZ></inist:fA14><country>Finlande</country><wicri:noRegion>department of Clinical Medicine, Unit of Neurology, Kuopio University</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Department of Pathology, Kuopio University Hospital</s1><s2>Kuopio</s2><s3>FIN</s3><sZ>2 aut.</sZ></inist:fA14><country>Finlande</country><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Al Sarraj, Safa" sort="Al Sarraj, Safa" uniqKey="Al Sarraj S" first="Safa" last="Al-Sarraj">Safa Al-Sarraj</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>MRC Neurodegenerative Brain Bank, Institute of Psychiatry, Kings College</s1><s2>London</s2><s3>GBR</s3><sZ>3 aut.</sZ><sZ>15 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Arzberger, Thomas" sort="Arzberger, Thomas" uniqKey="Arzberger T" first="Thomas" last="Arzberger">Thomas Arzberger</name><affiliation wicri:level="4"><inist:fA14 i1="06"><s1>Institut für Neuropathologie und Prionforschung, Ludwig-Maximilians-Universität München</s1><s2>Munich</s2><s3>DEU</s3><sZ>4 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Bogdanovic, Nenad" sort="Bogdanovic, Nenad" uniqKey="Bogdanovic N" first="Nenad" last="Bogdanovic">Nenad Bogdanovic</name><affiliation wicri:level="3"><inist:fA14 i1="07"><s1>Department of NEUROTEC, Division of Geriatric Medicine, Karolinska Institute</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>5 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="08"><s1>Huddinge Brain Bank KFC, Karolinska Institute</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>5 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Capellari, Sabina" sort="Capellari, Sabina" uniqKey="Capellari S" first="Sabina" last="Capellari">Sabina Capellari</name><affiliation wicri:level="4"><inist:fA14 i1="09"><s1>Dipartimento di Scienze Neurologiche, Universitá di Bologna</s1><s2>Bologna</s2><s3>ITA</s3><sZ>6 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Bologne</settlement><region nuts="2" type="region">Émilie-Romagne</region></placeName><orgName type="university">Université de Bologne</orgName></affiliation></author><author><name sortKey="Ferrer, Isidro" sort="Ferrer, Isidro" uniqKey="Ferrer I" first="Isidro" last="Ferrer">Isidro Ferrer</name><affiliation wicri:level="3"><inist:fA14 i1="10"><s1>Institute of Neuropathology, IDIBELL-Hospital Universitari de Bellvitge, Hospitalet de Llobregat</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>7 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Gelpi, Ellen" sort="Gelpi, Ellen" uniqKey="Gelpi E" first="Ellen" last="Gelpi">Ellen Gelpi</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Institute of Neurology, Medical University of Vienna</s1><s2>Vienna</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>8 aut.</sZ><sZ>16 aut.</sZ></inist:fA14><country>Autriche</country><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Kovari, Viktor" sort="Kovari, Viktor" uniqKey="Kovari V" first="Viktor" last="Kövari">Viktor Kövari</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Former National Institute of Psychiatry and Neurology</s1><s2>Budapest</s2><s3>HUN</s3><sZ>1 aut.</sZ><sZ>9 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Hongrie</country><placeName><settlement type="city">Budapest</settlement><region nuts="2">Hongrie centrale</region></placeName></affiliation></author><author><name sortKey="Kretzschmar, Hans" sort="Kretzschmar, Hans" uniqKey="Kretzschmar H" first="Hans" last="Kretzschmar">Hans Kretzschmar</name><affiliation wicri:level="4"><inist:fA14 i1="06"><s1>Institut für Neuropathologie und Prionforschung, Ludwig-Maximilians-Universität München</s1><s2>Munich</s2><s3>DEU</s3><sZ>4 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Nagy, Zoltan" sort="Nagy, Zoltan" uniqKey="Nagy Z" first="Zoltan" last="Nagy">Zoltan Nagy</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Former National Institute of Psychiatry and Neurology</s1><s2>Budapest</s2><s3>HUN</s3><sZ>1 aut.</sZ><sZ>9 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Hongrie</country><placeName><settlement type="city">Budapest</settlement><region nuts="2">Hongrie centrale</region></placeName></affiliation></author><author><name sortKey="Parchi, Piero" sort="Parchi, Piero" uniqKey="Parchi P" first="Piero" last="Parchi">Piero Parchi</name><affiliation wicri:level="4"><inist:fA14 i1="09"><s1>Dipartimento di Scienze Neurologiche, Universitá di Bologna</s1><s2>Bologna</s2><s3>ITA</s3><sZ>6 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Bologne</settlement><region nuts="2" type="region">Émilie-Romagne</region></placeName><orgName type="university">Université de Bologne</orgName></affiliation></author><author><name sortKey="Seilhean, Danielle" sort="Seilhean, Danielle" uniqKey="Seilhean D" first="Danielle" last="Seilhean">Danielle Seilhean</name><affiliation wicri:level="3"><inist:fA14 i1="11"><s1>Neuropathology Department, Pitié-Salpêtrière, AP-HP, Pierre and Marie Curie University</s1><s2>Paris</s2><s3>FRA</s3><sZ>13 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Soininen, Hilkka" sort="Soininen, Hilkka" uniqKey="Soininen H" first="Hilkka" last="Soininen">Hilkka Soininen</name><affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Department of Neurology, Kuopio University Hospital</s1><s2>Kuopio</s2><s3>FIN</s3><sZ>14 aut.</sZ></inist:fA14><country>Finlande</country><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Troakes, Claire" sort="Troakes, Claire" uniqKey="Troakes C" first="Claire" last="Troakes">Claire Troakes</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>MRC Neurodegenerative Brain Bank, Institute of Psychiatry, Kings College</s1><s2>London</s2><s3>GBR</s3><sZ>3 aut.</sZ><sZ>15 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Budka, Herbert" sort="Budka, Herbert" uniqKey="Budka H" first="Herbert" last="Budka">Herbert Budka</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Institute of Neurology, Medical University of Vienna</s1><s2>Vienna</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>8 aut.</sZ><sZ>16 aut.</sZ></inist:fA14><country>Autriche</country><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author></analytic><series><title level="j" type="main">Dementia and geriatric cognitive disorders</title><title level="j" type="abbreviated">Dement. geriatr. cogn. disord.</title><idno type="ISSN">1420-8008</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Dementia and geriatric cognitive disorders</title><title level="j" type="abbreviated">Dement. geriatr. cogn. disord.</title><idno type="ISSN">1420-8008</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Alzheimer disease</term><term>Anatomic pathology</term><term>Cardiovascular disease</term><term>Cognitive disorder</term><term>Degenerative disease</term><term>Encephalon</term><term>Europe</term><term>Nervous system diseases</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Démence d'Alzheimer</term><term>Pathologie de l'appareil circulatoire</term><term>Pathologie du système nerveux</term><term>Trouble cognitif</term><term>Maladie dégénérative</term><term>Encéphale</term><term>Anatomopathologie</term><term>Europe</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background: Dementia results from heterogeneous diseases of the brain. Mixed disease forms are increasingly recognized. Methods: We performed a survey within brain banks of BrainNet Europe to estimate the proportion of mixed disease forms underlying dementia and age- and gender-specific influences. Results: Data collected in 9 centres from 3,303 individuals were analysed. The proportion of patients with mixed diagnoses among all cases with Alzheimer disease (AD), vascular pathology (VP), argyrophilic grain dementia (AGD), and synucleinopathies, such as Lewy body dementia (LBD), Parkinson disease (PD) and synuclein pathology only in the amygdala, was 53.3%. Mixed pathology was more frequently reported with LBD, PD, AGD, and VP than with AD. The percentage of mixed diagnoses for AGD and VP significantly differed between centres. In patients younger than 75 years, synucleinopathies, and pure forms of AD, VP, and AGD were more frequent in men. Above 75 years of age, more women had pure AD and pure AGD. Conclusions: The most obvious neuropathological alteration should not terminate the diagnostic procedure since copathology is likely to be found. Neuropathological interpretation of AGD and VP has not been sufficiently established in a consensus. Pure forms of synucleinopathies are unlikely sole substrates for dementia.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Autriche</li><li>Espagne</li><li>Finlande</li><li>France</li><li>Hongrie</li><li>Italie</li><li>Royaume-Uni</li><li>Suède</li></country><region><li>Angleterre</li><li>Bavière</li><li>Catalogne</li><li>District de Haute-Bavière</li><li>Grand Londres</li><li>Hongrie centrale</li><li>Svealand</li><li>Vienne (Autriche)</li><li>Émilie-Romagne</li><li>Île-de-France</li></region><settlement><li>Barcelone</li><li>Bologne</li><li>Budapest</li><li>Londres</li><li>Munich</li><li>Paris</li><li>Stockholm</li><li>Vienne (Autriche)</li></settlement><orgName><li>Université Louis-et-Maximilien de Munich</li><li>Université de Bologne</li></orgName></list><tree><country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="Kovacs, Gabor G" sort="Kovacs, Gabor G" uniqKey="Kovacs G" first="Gabor G." last="Kovacs">Gabor G. Kovacs</name></region><name sortKey="Budka, Herbert" sort="Budka, Herbert" uniqKey="Budka H" first="Herbert" last="Budka">Herbert Budka</name><name sortKey="Gelpi, Ellen" sort="Gelpi, Ellen" uniqKey="Gelpi E" first="Ellen" last="Gelpi">Ellen Gelpi</name></country><country name="Hongrie"><region name="Hongrie centrale"><name sortKey="Kovacs, Gabor G" sort="Kovacs, Gabor G" uniqKey="Kovacs G" first="Gabor G." last="Kovacs">Gabor G. Kovacs</name></region><name sortKey="Kovari, Viktor" sort="Kovari, Viktor" uniqKey="Kovari V" first="Viktor" last="Kövari">Viktor Kövari</name><name sortKey="Nagy, Zoltan" sort="Nagy, Zoltan" uniqKey="Nagy Z" first="Zoltan" last="Nagy">Zoltan Nagy</name></country><country name="Finlande"><noRegion><name sortKey="Alafuzoff, Irina" sort="Alafuzoff, Irina" uniqKey="Alafuzoff I" first="Irina" last="Alafuzoff">Irina Alafuzoff</name></noRegion><name sortKey="Alafuzoff, Irina" sort="Alafuzoff, Irina" uniqKey="Alafuzoff I" first="Irina" last="Alafuzoff">Irina Alafuzoff</name><name sortKey="Soininen, Hilkka" sort="Soininen, Hilkka" uniqKey="Soininen H" first="Hilkka" last="Soininen">Hilkka Soininen</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Al Sarraj, Safa" sort="Al Sarraj, Safa" uniqKey="Al Sarraj S" first="Safa" last="Al-Sarraj">Safa Al-Sarraj</name></region><name sortKey="Troakes, Claire" sort="Troakes, Claire" uniqKey="Troakes C" first="Claire" last="Troakes">Claire Troakes</name></country><country name="Allemagne"><region name="Bavière"><name sortKey="Arzberger, Thomas" sort="Arzberger, Thomas" uniqKey="Arzberger T" first="Thomas" last="Arzberger">Thomas Arzberger</name></region><name sortKey="Kretzschmar, Hans" sort="Kretzschmar, Hans" uniqKey="Kretzschmar H" first="Hans" last="Kretzschmar">Hans Kretzschmar</name></country><country name="Suède"><region name="Svealand"><name sortKey="Bogdanovic, Nenad" sort="Bogdanovic, Nenad" uniqKey="Bogdanovic N" first="Nenad" last="Bogdanovic">Nenad Bogdanovic</name></region><name sortKey="Bogdanovic, Nenad" sort="Bogdanovic, Nenad" uniqKey="Bogdanovic N" first="Nenad" last="Bogdanovic">Nenad Bogdanovic</name></country><country name="Italie"><region name="Émilie-Romagne"><name sortKey="Capellari, Sabina" sort="Capellari, Sabina" uniqKey="Capellari S" first="Sabina" last="Capellari">Sabina Capellari</name></region><name sortKey="Parchi, Piero" sort="Parchi, Piero" uniqKey="Parchi P" first="Piero" last="Parchi">Piero Parchi</name></country><country name="Espagne"><region name="Catalogne"><name sortKey="Ferrer, Isidro" sort="Ferrer, Isidro" uniqKey="Ferrer I" first="Isidro" last="Ferrer">Isidro Ferrer</name></region></country><country name="France"><region name="Île-de-France"><name sortKey="Seilhean, Danielle" sort="Seilhean, Danielle" uniqKey="Seilhean D" first="Danielle" last="Seilhean">Danielle Seilhean</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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